The WAE Forward Podcast

The Iron–Hormone–Thyroid Triad of Fatigue.


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Fatigue is one of the most common — and most misunderstood — symptoms women experience. If you’re exhausted despite doing “all the right things,” this episode will help you understand why.

In this conversation, we explore The Iron–Hormone–Thyroid Triad of Fatigue through a functional medicine lens and explain how these three systems work together to regulate energy, metabolism, mood, and resilience. When one part of the triad is under stress, the others quickly follow — leading to persistent fatigue that sleep, caffeine, or willpower can’t fix.

You’ll learn why fatigue is not a personal failure, but a biological signal that your body is adapting to stress and asking for support.

  • Why fatigue is rarely caused by just one issue

  • The role iron plays in oxygen delivery, thyroid function, and cellular energy

  • How stress hormones and sex hormones influence iron loss and thyroid signaling

  • Why heavy cycles, low progesterone, and chronic stress drain energy

  • How the thyroid acts as your metabolic thermostat

  • Why “normal labs” don’t always reflect optimal function

  • The common cycle that keeps women stuck in survival mode

  • What your fatigue is actually trying to communicate

Rather than chasing symptoms, functional medicine looks at patterns, connections, and root causes. This episode explains how restoring iron stores, supporting hormone balance, regulating stress physiology, and optimizing thyroid conversion can help the body regain sustainable energy — without pushing harder or burning out.

  • Women who feel chronically tired or depleted

  • Those with “normal” labs but persistent symptoms

  • Anyone navigating hormonal changes, stress, or metabolic slowdown

  • Women who want to understand their body instead of fighting it

Your body isn’t broken — it’s responding intelligently to stress. When you understand the Iron–Hormone–Thyroid Triad of Fatigue, you can begin rebuilding energy in a way that feels safe, steady, and sustainable.



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The WAE Forward PodcastBy Angela Herren, Wellness Coach