With the first week of the 2021 pro football season in the books, we turn our attention to a live look at NFL Week 2 lines at leading US sportsbooks.

The Week 2 slate will kick off with a traditional NFC East slugfest between the Giants and Washington in the Nation’s Capital on Thursday night, with each club looking to bounce back from season-opening stumbles. Sunday and Monday night bring plenty of intrigue as well, with the Rams versus Colts, Bills versus Dolphins, 49ers versus Eagles and Chiefs versus Ravens matchups standing out.