Are your afternoon crashes, sudden irritability, or unstoppable sugar cravings trying to tell you something? In this episode we uncover how daily glucose swings—even in people without diabetes—contribute to fatigue, brain fog, mood issues, and accelerated aging. Most importantly, we translate the best evidence into five simple hacks you can use today to flatten the curve and feel incredible.

What you’ll learn:

• What glycemic variability is and why A1c can miss it

• How meal order, movement, sleep, stress, caffeine timing, and hormones shape your curve

• Why swings drive oxidative stress, vascular damage, cravings, mood shifts, and insulin resistance

• Five simple curve‑flattening habits you can implement immediately

• A one‑week listener challenge to feel measurable changes

Listener Challenge: Pick one hack for seven days: 10‑minute walk after meals; protein + fiber first; add vinegar; flip breakfast; win the 3 p.m. window. Share your results with me on Instagram.

00:00 — Cold Open

01:00 — What is glycemic variability?

06:00 — What causes glucose swings?

15:00 — Why spikes accelerate aging

25:00 — Five hacks to flatten the curve

38:00 — Listener challenge + wrap

40:00 — Outro

Citations:

• Monnier L, et al. Glucose variability and oxidative stress. J Diabetes Sci Technol. 2006.

• Shukla AP, et al. Food order has a significant impact on postprandial glucose and insulin levels. Diabetes Care. 2015.

• DiPietro L, et al. Short postmeal walks reduce glycemic response. Med Sci Sports Exerc. 2013.

• Johnston CS, et al. Vinegar ingestion at mealtime moderates postprandial hyperglycemia and insulin. Ann Nutr Metab. 2010.

• Additional supporting literature on sleep, stress, caffeine timing, hormonal effects, and individualized responses referenced in the episode narrative.

For up to 15% off on Fullscript supplements via The Longevity Link:

https://us.fullscript.com/welcome/thelongevitylink

Website: www.thelongevitylink.com

Instagram: thelongevitylink_podcast

In this episode, compounding pharmacist Chris Givant, explores the surprising benefits of creatine beyond muscle strength. While often associated with gym-goers, creatine offers numerous advantages for bone health, brain function, and longevity. Creatine's role as a cellular power molecule makes it essential for anyone looking to age vibrantly. With endorsements from longevity experts and studies highlighting its use among athletes, creatine proves beneficial for all regardless of age or athletic involvement. As a safe supplement, creatine can enhance muscle mass, bone density and brain support with minimal daily intake, making it a powerful addition to your wellness and longevity gameplan.

For up to 15% off on Fullscript supplements via The Longevity Link:

https://us.fullscript.com/welcome/thelongevitylink

Have a question? Leave your question in the "chat" and we'll get back to you as soon as possible.

Website: www.thelongevitylink.com

Instagram: thelongevitylink_podcast

Sarcopenia, the age-related loss of muscle mass and strength, is a common and potentially dangerous condition as we age. This podcast episode, hosted by compounding pharmacist Chris Givant, explores the importance of muscle maintenance for longevity. Chris emphasizes that regular activities like walking the dog or doing yoga are not enough to preserve muscle. Instead, a focus on strength training, proper nutrition, and lifestyle adjustments is essential. Chris discusses testing you can do at home for muscle loss. She discusses supplements, hormones, and exercises that can help combat muscle loss and enhance overall health, ultimately promoting independence and a better quality of life in later years.

For up to 15% off on Fullscript supplements via The Longevity Link; https://us.fullscript.com/welcome/thelongevitylink

Website: www.thelongevitylink.com

Instagram: thelongevitylink_podcast

In this podcast episode, host Chris Kavant delves into the intriguing possibility that Ozempic, known generically as semaglutide, might do more than aid weight loss. Beyond its primary use as a diabetes medication, semaglutide shows promise in extending both healthspan and lifespan by reducing major cardiovascular risks. The episode explores key scientific studies, including the groundbreaking Select trial, revealing that Ozempic may significantly reduce heart attacks and strokes, moving it beyond a simple weight loss aid to a potential lifesaver, especially for those with obesity but without diabetes.

For up to 15% off on Fullscript supplements via The Longevity Link:

https://us.fullscript.com/welcome/thelongevitylink

Website: www.thelongevitylink.com

Instagram: thelongevitylink_podcast

This is an encore presentation of The Longevity Link's most popular episode!

In the first episode of season 2 of 'Not Your Mother's Hormones' we tackle thequestion: Is drinking alcohol really all that bad for you? This conversation revolves around alcohol and its implications on health and wellness. It provides insights into the meaning of a standard unit of alcohol in the U.S. and defining what constitutes a light, moderate, or heavy drinker.

Christine the Hormone Queen delves into the latest studies and helps to break down the often confusing evidence regarding alcohol and it's effects on your brain, your cardiovascular system, and on the risk for cancer.

Sometimes the latest studies seem to contradict themselves, so Christine dives in and ferrets out the differentiating factors and helps you to truly understand alcohol and it's effects, good and bad, on the body.

You won't want to miss this episode!

The Longevity Link podcast episode hosted by Chris Givant focuses on the growing popularity of cold and heat exposure therapies like ice baths and saunas. Chris explains the science behind these methods, highlighting how they can enhance physical resilience, mental well-being, and metabolic health through processes such as norepinephrine release and mitochondrial biogenesis. The episode provides actionable guidance on optimal temperatures, durations, and frequencies for safe and effective cold and hot therapy practices. Chris also underscores the importance of exercising caution and seeking medical advice if necessary, offering listeners a balanced view of how to incorporate these potentially powerful tools into their wellness routines.

In this episode of The Longevity Link, host Chris Givant delves into the critical predictors of a long and healthy life. She highlights the importance of VO2 max, muscle mass, particularly leg strength, and metabolic health. Givant dispels common myths around VO2 max, emphasizing its significance beyond just elite athletes. The discussion also covers strategies for improving VO2 max through zone 2 and HIIT training, offering listeners practical advice on integrating these methods for optimal health span. Chris explains in detail how to improve all 3 of these markers of longevity. Also included are "extra" predictors such as grip strength and gait speed. You won't want to miss this one!

For up to 15% off on Fullscript supplements via The Longevity Link:

https://us.fullscript.com/welcome/thelongevitylink

Website: www.thelongevitylink.com

Instagram: thelongevitylink_podcast

In this episode of the Longevity Link, host Chris Givant explores the impact of senescent cells, also known as zombie cells, on the aging process and overall health. These cells, which refuse to die and instead linger in the body, release damaging chemicals contributing to aging and various diseases. Chris discusses cutting-edge research involving drugs called senolytics and senomorphic agents, which aim to curb the adverse effects of these cells.

Clinical research and The Hit and Run dosing schedule are discussed along with discussing which senlytics are available currently.

For up to 15% off on Fullscript supplements via The Longevity Link:

https://us.fullscript.com/welcome/thelongevitylink

Website: www.thelongevitylink.com

Instagram: thelongevitylink_podcast

On this episode of The Longevity Link host Chris Givant discusses low libido with Dr. Brooke Leverone. Dr. Leverone explains that low libido and low frequency of sex can happen to most couples at some point. Causes range from hormones, past traumas, stress, medications, health issues, relationship issues/resentments, familiarity, social media, and even the use of porn.

Chris and Dr Leverone also discuss sex-less relationships and state if both partners are satisfied with the dynamic and have other sources of intimacy such as cuddling, holding hands or hugging, then a couple can still enjoy a healthy and happy relationship. It only becomes a problem for a couple if one or both partners have any distress over it.

Chris and Dr. Leveone go on to provide actionable items to employ to get your desire and your sex life back again.

To contact Dr. Brooke Leverone:

drbrookeleverone.com

To order her female hormone testing for perimenopausal/menopausal patients:

https://go.drbrookeleverone.com/get-your-life-back

For up to 15% off on Fullscript supplements via The Longevity Link:

https://us.fullscript.com/welcome/thelongevitylink

Website: www.thelongevitylink.com

Instagram: thelongevitylink_podcast

Studies:

· Twenge, J. M., Sherman, R. A., & Wells, B. E. (2017). Declines in sexual frequency among American adults, 1989–2014. Archives of Sexual Behavior, 46(8), 2389–2401. https://doi.org/10.1007/s10508-017-0953-1

· Wu, F. C., Tajar, A., Pye, S. R., Silman, A. J., Finn, J. D., O’Neill, T. W., … & Forti, G. (2010). Hypothalamic-pituitary-testicular axis disruptions in older men are linked to ill health, not aging: The European Male Aging Study. Journal of Clinical Endocrinology & Metabolism, 95(4), 1810-1818. https://doi.org/10.1210/jc.2009-1796

· Kingsberg, S. A., Clayton, A. H., & Simon, J. A. (2015). Female sexual dysfunction—Medical and pharmacological treatment indications. Therapeutic Advances in Endocrinology and Metabolism, 6(2), 67–79. https://doi.org/10.1177/2042018814565858

· Mark, K. P. (2012). The relative impact of individual sexual desire and couple desire discrepancy on satisfaction in heterosexual couples. Sexual and Relationship Therapy, 27(2), 133–146. https://doi.org/10.1080/14681994.2012.678825

· Umberson, D., Thomeer, M. B., Kroeger, R. A., Lodge, A. C., & Xu, M. (2015). Challenges and opportunities for research on same-sex relationships. Journal of Marriage and Family, 77(1), 96–111. https://doi.org/10.1111/jomf.12155

· Blair, K. L., & Pukall, C. F. (2014). Family structure and sexuality: Comparing sexual behavior and outcomes among lesbian, gay, and heterosexual individuals. Journal of Sex Research, 51(7), 703–715. https://doi.org/10.1080/00224499.2013.806652

· Wright, P. J., Tokunaga, R. S., & Kraus, A. (2016). Consumption of pornography, perceived partner expectations, and sexual satisfaction among heterosexual men and women. Archives of Sexual Behavior, 45(1), 77–89. https://doi.org/10.1007/s10508-015-0564-0

In this episode of the Longevity Link podcast, host Chris Givant welcomes hormone expert Dr. Janette Gray MD to discuss the complex world of hormones and how they impact our health. The conversation delves into the benefits of hormone replacement therapy (HRT), particularly for women facing menopause or perimenopause. Dr. Gray shares insights from her extensive experience, aiming to debunk myths and provide clarity on HRT's role in enhancing both lifespan and healthspan. Through her 'Wellness Wheel' concept and personal anecdotes, Dr. Gray emphasizes the importance of considering lifestyle choices alongside medical treatments for optimal health.

For up to 15% off on Fullscript supplements:

https://us.fullscript.com/welcome/thelongevitylink

Website: www.thelongevitylink.com

Instagram: thelongevitylink_podcast

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