The central message of this sermon is that true prayer addresses the true God by recognizing His supremacy and desiring to align one's will with His. The speaker argues that if we pray in accordance with who God is, rather than trying to manipulate or control Him through repetitive words or selfish requests, we can have a deep and meaningful relationship with Him. This requires acknowledging our place as part of a community, recognizing the supremacy of God's person, program, and will, and seeking to be part of His kingdom by allowing Him to work in us and through us. The speaker encourages listeners to pray with simplicity, balance, and reverence, asking for things that align with who Jesus is, rather than trying to use prayer as a means to achieve personal gain or desires. Ultimately, the sermon emphasizes the importance of recognizing God's true nature and praying in accordance with His will, which can lead to a deeper sense of communion and relationship with Him.