The National Cancer Institute defines the 'lost generation' of cancer patients as adolescent and young adult patients 15 to 39 years of age. These patients have demonstrated lower rates of improvements in survival and the lowest rate of participation in federally-funded clinical trials. Host Dr. Jerome Lisk talks with Dr. David Freyer, director of the LIFE Survivorship and Transition Program at Children's Hospital Los Angeles, about the challenges facing this group of cancer patients.