In this episode of THE PIBD DIGEST, Dr Tracy Coelho and Dr Chris Bakewell welcome a true heavyweight in the world of monogenic IBD, Dr Jochen Kammermeier- a paediatric gastroenterologist at Evelina Children’s Hospital, London, and bona fide gene whisperer, who helps us untangle the twisted helix of monogenic IBD. Expect a deep dive into sharp gene talk and insightful immunology, and — of course — our signature poetic showdown. This week: Dr Coelho’s lyrical face-off, “A Tale of Two Adversities”, where monogenic and polygenic IBD battle it out in verse.