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The Miller-Urey Experiment


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Imagine for a moment that you're back in a time when the Earth was still formed but life didn't yet exist. The sky's filled with thunder, lightning, and the atmosphere's a toxic soup of methane, ammonia and other gases -- it certainly doesn't seem like a setting where life could blossom.

That’s where scientists Stanley Miller and Harold Urey step in. In the 1950s, they set out to demonstrate a groundbreaking idea: that life, or the building blocks of life, could have spontaneously arisen under these harsh conditions.
Their experiment was simple in design. They created a mini 'Earth' in the laboratory, consisting of a sealed flask filled with water (to represent oceans), which was heated to make water vapor. This vapor traveled up into a second flask with those toxic gases which was stirred to simulate the Earth’s atmosphere. Any lightning in this ‘atmosphere’ was mimicked using electrical sparks. Chemical reactions probably took place and then the mixture cooled, allowing the newly formed molecules to rain back down into the heated flask - just like on early Earth.
The secret sauce to this experiment was patience; they let this cycle continue for a week. After that, they discovered something extraordinary in the liquid in the flask: amino acids, the fundamental building blocks of life.
This was huge because it suggested that simple organic molecules -- the raw materials for life -- could self-assemble under Earth's early conditions. It was kind of like proving that if you tossed LEGO blocks in a tumble dryer long enough, they might eventually click together to form a LEGO replica of a tree or a house.
The Miller-Urey experiment was a significant leap forward in our understanding of how life might have begun, although it didn't replicate the complete origin of life. There's a big difference between a pile of LEGO bricks (even if in the form of a tree or house) and a living, growing, reproducing tree. The experiment didn't create life: it created basic building blocks for life, and just one type (amino acids), leaving still unsolved the mystery of how these molecules could self-assemble into functional, living organisms.
In conclusion, the Miller-Urey experiment provided key evidence supporting the theory of abiogenesis, the idea that life rose from non-living matter. It suggested that basic organic building blocks could indeed spontaneously form under the conditions thought to be present on the early Earth. However, the jump from these basic building blocks to the complex, reproducing entities that constitute life remains a puzzle yet to be fully solved.

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TIL: ELI5By TIL