In this episode of the Soberhead Podcast, Dr. Esra Çavuşoğlu, PhD welcomes Dr. Anurag Singh MD PhD. Dr. Anurag Singh MD PhD, physician scientist, immunologist, and chief medical officer of Timeline Nutrition.
In this episode, Dr. Singh explains the science behind urolithin A, the key compound in Timeline Nutrition’s Mitopure, and why it has become such an important molecule in longevity research. He describes urolithin A as a postbiotic produced by the gut microbiome from compounds found in pomegranate, walnuts, and pecans but notes that most people do not produce enough of it naturally. Its main role is to support mitophagy, the process of clearing out damaged “zombie” mitochondria so healthier mitochondria can function more efficiently, improving cellular energy, muscle function, recovery, and potentially inflammation. The conversation focuses heavily on muscle aging, mitochondrial health, immune function, and healthy longevity.
Dr. Singh shares that clinical trials have shown benefits in older adults, athletes, and midlife adults, including improvements in muscle endurance, strength, recovery, and inflammatory markers. He also discusses emerging research on the immune system, skin, and brain health, while emphasizing that urolithin A is not a magic pill but a science-backed foundational supplement that may work best alongside exercise, good nutrition, and other core longevity habits.
#EsraÇavuşoğlu #AyıkKafa #ElevatingLifeEvolvingHealth #Longevilab #AnuragSingh

Dr. Anurag Singh, MD, PhD Website: https://www.researchgate.net/profile/Anurag-Singh-89
Special thanks to T.C. Istanbul Gedik University https://www.gedik.edu.tr/en/

00:00-02:49 Introduction.
02:49-07:50 Who is Dr. Anurag
07:50-10:14 What is urolithin A?
10:14-11:40 Prebiotic, probiotic, postbiotic explained
11:40- 13:25 How urolithin A works on mitochondria
13:25-15:50 Sarcopenia, muscle aging & strength
15:50-19:18 Does it work without exercise?
19:18- 20:03 Muscle quality vs muscle size
20:03- 23:52 Immune system effects
23:52- 24:27 Why top longevity experts pay attention to it
24:27- 26:09 Can you make urolithin A from food alone?
26:09-27:34 Brain health research
27:34- 29:16 Is it a senolytic?
29:16- 33:38 500 mg vs 1000 mg
33:38-37:05 Longevity supplement overload
37:05-38:53 What happens if damaged mitochondria are not cleared?
38:53-40:36 XPrize & longevity innovatio
40:36-43:00 Skin, collagen & topical use
43:00-43:50 Wrap up.

*About Ayık Kafa*
Dr. Esra Çavuşoğlu, PhD, took her studies, starting from her personal treatment experiences and continuing with her clinical psychology education, to the next level by completing her PhD focused on Addiction. Dr. Esra in Ayık Kafa podcast discusses the world’s latest technologies, protocols, products and research in the fields of Biohacking and Longevity, while sharing first-hand information and experiences about the Disease of Addiction, as well as her latest academic studies.

*About Dr. Esra Çavuşoğlu, PhD*
Longevilab’s founder, Dr. Esra, is a United States and internationally trained clinical psychologist and a certified addiction therapist in New York. She served as International Development Advisor on the Yale University Faculty of Medicine Clinical Advisory Board. She is the founder and supervisor of Gaziantep Oya Bahadır Yüksel Rehabilitation Center, Dr. Esra is the designer and implementer of the Turkey Rehabilitation Model. Dr. Esra founded the Contemporary Addiction Studies Association (ÇABAÇAD) in order to combat Turkey’s growing addiction problem.

Disclaimer
The information and statements on our YouTube Channel Sober-Head are not intended to guide individuals towards medical diagnosis and treatment.Please consult with your doctor for medical diagnostic and treatment procedures.The content is shared for informational purposes only, derived from scientific studies prepared by EMC Medya Yayıncılık Ticaret Ltd. Şti.’s researchers, consultants, and authors/scientists, as well as compilations from publicly available public