In the second part of this two part episode, Dr. P and Dr. K discuss the opioid epidemic that has swept the nation, starting from the 1990s. This episode focuses on the aftermath of the opioid crisis and the future of opioid prescribing in the U.S. from the viewpoint of two pain physicians. In this episode, we discuss new measures for safe opioid prescribing as well as interventional and alternative therapies and advancements in the field of pain medicine.