Joint discomfort, sore muscles, restless nights, and being overwhelmed by daily stress seem like separate challenges — but did you know your body naturally makes a nutrient that offers support for all of them?

In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a deep dive into PEA (palmitoylethanolamide)—a naturally occurring fatty compound your body uses to manage discomfort, stress, and support a healthy inflammation response.

Carl explains how PEA levels tend to decline with age (when we need PEA most), why most PEA supplements fall short, and how the best studied form of PEA, called Levagen+, overcomes absorption challenges and delivers results using the novel LipiSperse delivery technology. With over 14 published human studies, Levagen+ has been shown to support joint comfort, flexibility, muscle recovery, sleep quality, cognitive performance, immune health, and more.

This is why we made Levagen+ a cornerstone ingredient in TrueJoint FLX, NatureCity’s premium joint formula, which was designed to help you start feeling better within days — and help keep you mobile and active with better joint function over time.

If you want to support joint health, recover faster, sleep better, and support long-term resilience as you age, this episode is a must-listen.

WHAT YOU’LL LEARN

What PEA is and how your body naturally uses it

PEA production declines with age — so supplementation makes sense

Why Levagen®+ is the best PEA for supplements

1. Research-backed benefits for joint comfort and flexibility
2. How Levagen+ supports faster muscle recovery and performance
3. The role PEA plays in sleep quality, stress support, and cognition
4. Emerging research on immune, gut, metabolic, and menstrual support
5. Why NatureCity includes Levagen+ in its TrueJoint FLX formula

TIMESTAMPS

0:00 – Welcome & why PEA deserves attention

1:04 – What PEA is and where it comes from

1:51 – PEA levels decline with age

2:15 – The absorption problem with standard PEA supplements

2:38 – Why Levagen®+ is different

3:02 – LipiSperse® technology & absorption benefits

3:30 – Joint comfort, stiffness, and flexibility research

4:40 – Muscle recovery, soreness, and performance support

5:42 – Sleep quality, stress balance, and nervous system support

6:15 – Cognition, BDNF, and mental alertness findings

6:58 – Heart rate variability support & stress resilience

7:21 – Emerging research: menstrual comfort, gut & metabolic health

8:04 – Final thoughts & where to learn more

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