The Pediatric and Developmental Pathology Podcast

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Tetyana Nesterenko, Neonatologist in the Division of Neonatal-Perinatal Medicine at UT Southwestern Medical Center, affiliated with Dallas Children's Hospital; Dr. Evelyn Ilori, Hematopathology Fellow at UT Southwestern; Dr. Christine Kahlow, PGY-3 Resident at UT Southwestern; and Dr. Charles Timmons, Pediatric Pathologist and faculty at UT Southwestern, based at Children's Medical Center.

Hear how a multidisciplinary team at UT Southwestern approached a full-term neonate's unexplained, rapidly fatal respiratory failure, from the resuscitation and family communication in the NICU to an autopsy that uncovered severe pulmonary hypoplasia and congenital alveolar dysplasia. A standard genetic sequencing panel came back normal, but chromosomal microarray analysis revealed the true cause: a deletion encompassing the TBX4 gene. We discuss the collaboration of their team to identify TBX4 haploinsufficiency at autopsy, and their article in Pediatric and Developmental Pathology:

Primary Pulmonary Hypoplasia With Congenital Alveolar Dysplasia Associated With TBX4 Gene Deletion: A Case With Autopsy and Molecular Findings

Featured public domain music: Summer Pride by Loyalty Freak

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Sanjita Ravishankar, a Pediatric, Perinatal, and Gynecologic Pathologist at University Hospitals Cleveland Medical Center and Case Western Reserve University School of Medicine, who led the Society for Pediatric Pathology's Placental Pathology Reporting Task Force; Dr. Philip Katzman, a Pediatric and Perinatal Pathologist at the University of Rochester Medicine; Dr. Karen Mestan, Professor of Pediatrics and Division Chief of Neonatology at the University of California San Diego and Rady Children's Hospital; and Alicia Loehlein, co-founder of the nonprofit organization Measure the Placenta (@measuretheplacenta).

Hear how a multidisciplinary task force of the Society for Pediatric Pathology (@SocPediPath), including pathologists, obstetric and neonatology clinicians, and patient advocates worked together to build a standardized placental pathology reporting template designed to complement the Amsterdam consensus definitions as we discuss their article in Pediatric and Developmental Pathology:

Standardized Placental Pathology Reporting: Improving Quality and Clinical Utility Recommendations From the Society for Pediatric Pathology Placental Pathology Reporting Task Force

Learn more about the patient advocacy work discussed in this episode:

Measure the Placenta: measuretheplacenta.org | Instagram: @measuretheplacenta

Featured public domain music: Summer Pride by Loyalty Freak

In this special episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Bev Rogers of the University of Arizona and Banner Health, Dr. Raj Kapur of Seattle Children's Hospital, Dr. Linda Ernst of Endeavor Health and the University of Chicago, and Dr. Miguel Reyes-Múgica of the University of Miami and Holtz Children's Hospital.

Hear about the Perspectives In Pediatric Pathology series from the history of Perspectives In Pediatric Pathology and how it became part of Pediatric and Developmental Pathology, to the current issue of Perspectives featuring articles on fetal and placental pathology for the general pathologist in Pediatric and Developmental Pathology:

Perinatal Pathology for the General Pathologist - A Practical Guide to Fetal and Placental Examination

Featured public domain music: Summer Pride by Loyalty Freak

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Sonja Chen (X: @IslandJewelsena, LinkedIn: Sonja Chen and Instagram: @pediatricpathologyadventurer), Director of Autopsy Services and Program Director for the Pediatric Anatomic Pathology Fellowship at Nationwide Children's Hospital and Dr. Oscar Lopez-Nunez (@olopeznu), Pediatric Pathology Fellowship Program Director at Cincinnati Children's Hospital.

Hear how social media has shaped careers, collaborations, and the visibility of pediatric pathology, as well as what the field stands to gain by embracing Social Media more fully, as we discuss their article in Pediatric and Developmental Pathology:

Exploring the Impacts and Prospects of Social Media in Advancing Pediatric Pathology

Featured public domain music: Summer Pride by Loyalty Freak

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Peilin Zhang, a Pathologist at Sharp Memorial Hospital in San Diego, California.

Hear how building a database of placental pathology information led to the identification of unexpected correlations, and the article in Pediatric and Developmental Pathology:

Intervillous Thrombus Is Independently Associated With Placental Infarct and Single Umbilical Artery as well as Fetal Inflammatory Response: Implication of Fetal Vascular Flow in Pathogenesis

Featured public domain music: Summer Pride by Loyalty Freak

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Manas Kalra, a Pediatric Oncologist in the Department of Paediatric Haematology Oncology and BMT at Sir Ganga Ram Hospital in New Delhi, India and Dr. Neha Bakshi, a Histopathologist in the Department of Pathology, Histopathology Division, of Sir Ganga Ram Hospital in New Delhi, India.

Hear how a multidisciplinary approach identified a paratesticular presentation of a rare tumor, and their resulting article in Pediatric and Developmental Pathology:

“What the Mind Does Not Know, the Eye Does Not See”: Epididymal Melanotic Neuroectodermal Tumor of Infancy Misdiagnosed as Paratesticular Rhabdomyosarcoma—A Rare Case Report

Featured public domain music: Summer Pride by Loyalty Freak

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Aida Glembocki, a Pediatric Pathologist and Masters Degree candidate at the University of Toronto, and Dr. Robert Siddaway, an Oncology Investigator at The Hospital for Sick Children in Toronto.

Hear about how The Hospital for Sick Children applies RNA sequencing in pediatric cancer diagnosis to reduce costs and identify key information for diagnostic classification. We also hear about their article in Pediatric and Developmental Pathology:

Fusion-Negative Rhabdomyosarcoma: Clinical Application of Targeted RNA Sequencing

Related article:

Featured public domain music: Summer Pride by Loyalty Freak

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Lauren Miller (@LJMiller_MD), a 4th year AP/CP Pathology Resident at the University of Michigan; Dr. Amer Heider (@amerheider), Pediatric and Perinatal Pathologist at the University of Michigan; and Dr. Lina Shao, Cytogeneticist and Clinical Professor at the University of Michigan.

Hear about Pathology at the University of Michigan (https://www.pathology.med.umich.edu/) and training in Pediatric Pathology (https://www.pathology.med.umich.edu/index.php?t=page&id=1396). Find out how they triage tissue from pediatric cancers, and how that approach led to their article in Pediatric and Developmental Pathology:

A Novel GLCCI1::BRAF Fusion With Independent MYC and MYCN Amplifications in Pediatric Pancreatic Acinar Cell Carcinoma

Learn more about Pathology at the University of Michigan on social media:

X: @UMichPath

Insta: umichpath

Facebook: University of Michigan Department of Pathology

Featured public domain music: Summer Pride by Loyalty Freak

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Professor Matthew J. Murray of the Department of Pathology and the Department of Paediatric Haematology and Oncology at the University of Cambridge, Cambridge, UK; Consultant Pediatric Pathologist Claire Trayers of the Department of Histopathology at Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK; and Consultant Pediatric Oncologist Charlotte Burns of the Department of Paediatric Haematology and Oncology at Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Hear about how persistence and a serum biomarker for a miRNA helped identify a NUT carcinoma as we talk about their work and their article in Pediatric and Developmental Pathology:

Mediastinal NUT Carcinoma With Raised Serum Alpha-Fetoprotein Mimicking a Malignant Germ Cell Tumor: Suspicion Raised Due to Negative Serum miR-371a-3p Levels

Featured public domain music: Summer Pride by Loyalty Freak

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Mukul Vij of the Department of Pathology, Dr. Rela Institute & Medical Centre, Chennai, Tamil Nadu, India and with Dr. Vaibhav Shah, a Pediatric Gastroenterologist and Hepatologist at Gujarat Super Speciality Clinic, Ahmedabad, Gujarat, India.

Hear about an uncommon type of childhood cirrhosis that was first described in India, and how the incidence and recognition of this entity has changed over time as we talk about their article in Pediatric and Developmental Pathology:

Indian Childhood Cirrhosis: Report of 2 Cases With Review of Literature and Implication of Metallothionein Immunohistochemical Expression

Featured public domain music: Summer Pride by Loyalty Freak