Welcome back to The Popkin Method, where real medicine meets real results. In this episode, Dr. Matthew C. Popkin tackles one of the most overlooked health challenges: the "wired but tired" syndrome. If you’ve been struggling with poor sleep, chronic stress, brain fog, unexplained weight gain, or low motivation, this conversation is for you.

Dr. Matthew C. Popkin breaks down how sleep and stress create a vicious cycle that quietly wreaks havoc on your hormones, brain function, metabolism, and immune system. You'll learn why sleep is much more than just “rest”; it’s foundational to nearly every aspect of your health. Through real patient stories and science-backed insights, Dr. Matthew C. Popkin explains how the symptom spiral starts and, more importantly, how you can break free from it.

From practical tips on improving your sleep hygiene and stress resilience, to which supplements can make a real difference (and which habits might be sabotaging your nights), this episode is packed with actionable strategies. Whether you’re searching for ways to boost your daily energy, sharpen your focus, or finally get a restful night's sleep, Dr. Matthew C. Popkin shares his proven method to help you stop the cycle and reclaim your health.

Tune in and discover how fixing your sleep and stress can be the key to unlocking everything else and why sometimes, what you really need isn’t just another pill, but true sleep rehab.

Timestamps:

00:00 "Cortisol, Stress, Sleep Disruption"

09:54 "Sleep: The Key to Health"

15:43 Sleep: Key to Combating Burnout

17:57 Stress Disrupts Cortisol Rhythm

26:21 "Creatine, Sleep, and Brain Health"

29:56 "Improving Sleep with Cortisol Insights"

37:11 Sleep, Stress, and Hormones Analysis

42:37 Unhealthy Habits Disrupting Sleep

49:52 "Phone Radiation Impacts Sleep Quality"

53:25 Sleep Improvement Without Supplements

57:18 Mindfulness and Sleep Strategies

01:04:56 "Restoring Body's Natural Rhythm"

01:12:12 Sleep Aid Alternatives and Solutions

01:13:29 Sleep and Stress: Silent Drivers

You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected].

Podcast Website - https://thepopkinmethod.com/

Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

Podcast Partner - TopHealth - https://tophealth.care/

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome back to The Popkin Method, where real medicine meets real results. Have you ever left the doctor’s office feeling frustrated because your bloodwork was “normal,” but you still feel tired, foggy, or just not yourself? This episode is for you. Dr. Matthew C. Popkin reveals the four crucial labs that most physicians overlook: tests that could make all the difference between simply surviving and truly thriving. We’ll unpack why standard labs often miss the real issues, which advanced markers you should be asking for, and how understanding your unique bloodwork can unlock better energy, mental clarity, and long-term health. If you’re ready to go beyond the basics and get answers about your health that actually translate to results, you won’t want to miss this episode.

Timestamps:

00:00 Advanced Lipid Profiles for Heart Risk

05:06 Advanced Lipid Profiling for Heart Health

09:52 Gene Mutation Impacts Treatment Strategies

12:12 "Supplements for MTHFR Gene Mutation"

16:48 Advanced Testing for Heart and Mental Health

18:08 Personalized Medicine Through Genetic Testing

22:00 Navigating Medical Testing and Insurance

27:12 "Proactive Health: Beyond Insurance Limits"

29:04 Preventing Diabetes Through Early Intervention

You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected].

Podcast Website - https://thepopkinmethod.com/

Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

Podcast Partner - TopHealth - https://tophealth.care/

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome back to The Popkin Method, where we cut through the noise and deliver practical, personalized medicine insights that genuinely work. In this episode, host Layla sits down with Dr. Matthew Popkin to demystify one of the most confusing corners of the wellness world: supplements. Are they must-haves or just expensive placebos? Which ones are truly helpful, which are hyped, and which might even be harmful? Dr. Popkin peels back the marketing myths, shares his "Core Five" recommended supplements, and reveals how he incorporates them into real care plans alongside lifestyle, diet, and exercise, not as quick-fix solutions. Whether you’re debating that bottle of ashwagandha, worried about your protein intake, or overwhelmed by online supplement chatter, this episode is packed with clear, actionable advice and the clinical truths you won’t get from Instagram influencers. If you’re ready to build a supplement regimen that actually supports your health goals, you’re in the right place.

Timestamps:

00:00 Evolving Medical Approach: Supplements Included

04:56 Essential Supplements for Optimal Health

07:34 "Supplement Stacks for Better Sleep"

10:48 Beware Fake Supplements Online

16:27 NAD Therapy and Mitochondrial Health Trends

19:14 Creatine's Expanding Benefits and Dosages

22:15 Creatine's Effect on Body Composition

24:44 Evaluating Supplement Effectiveness

29:16 Core 5 Supplements Guide

32:36 "The Popkin Method: Smart Supplementation"

You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected].

Podcast Website - https://thepopkinmethod.com/

Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

Podcast Partner - TopHealth - https://tophealth.care/

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome back to The Popkin Method, where we cut through the noise to uncover what really works for your health. In today’s episode, host Matthew C. Popkin, M.D. shares an honest, nuanced

Matthew C. Popkin, M.D. explains why weight isn’t just about willpower or the latest diet trend; it’s a complex interplay of biology, hormones, lifestyle, and sometimes, medicine. He emphasizes compassion over shame, sharing insights from his medical practice and breaking down common myths, including the hype around GLP-1 medications like Ozempic and Mounjaro. The episode dives into the pitfalls of quick-fix solutions, the real risks of muscle loss on popular injectable medications, and most importantly, the comprehensive, individualized approach that’s the hallmark of The Popkin Method.

Whether you’ve struggled with weight or simply want to understand the latest treatments and holistic strategies, this episode will help you filter out the fads, get real about sustainable change, and start building a path to better health that doesn’t rely on “magic bullets” just science, support, and a method that actually listens to you.

00:00 Empathetic Weight Loss Physician

05:15 Weight Loss Scams and Real Solutions

09:01 Blood Glucose Regulation Dynamics

09:45 Obesity Drugs Go Beyond Weight Loss

13:08 Muscle Loss from Weight-Loss Medications

17:32 Exercise and Supplements for Muscle Maintenance

21:29 Optimize Hormones for Weight Loss

23:30 "Prioritize Muscle in Weight Loss"

26:53 Holistic, Personalized Weight Management

31:11 Holistic Health Solutions Overview

33:34 Hope Through Holistic Weight Management

36:31 Customized Sustainable Weight Loss Program

41:50 Weight Loss Assistance & Podcast

43:40 "Final Thoughts and Contact"

You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected].

Podcast Website - https://thepopkinmethod.com/

Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

Podcast Partner - TopHealth - https://tophealth.care/

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome to the very first episode of The Popkin Method - a show where real medicine meets real results. In this episode, host Matthew C. Popkin, M.D., a physician who’s on a mission to revolutionize healthcare by bridging the gaps that leave so many patients feeling lost, frustrated, and unheard. Dr. Popkin shares his personal journey from his early days dreaming of medicine to his extensive training at institutions like the University of Miami, Mount Sinai, and the Cleveland Clinic.

Dr. Popkin pulls back the curtain on the realities of modern medicine - fragmented care, information overload, and the struggle patients face between traditional and functional approaches. Dr. Popkin unpacks the story behind the Popkin Method: a patient-centered, compassionate blend of internal and functional medicine that aims to deliver answers, real improvement, and genuine connection.

If you've ever felt dismissed or overwhelmed by the healthcare system, this episode will leave you feeling seen, validated, and empowered. Tune in for heartfelt insights, practical advice, and a sneak peek at the groundbreaking topics coming up in future episodes, from weight loss and hormone therapy to peptides, pain management, and gut health.

Timestamps:

00:00 "Journey Between New York and Florida"

05:47 Closing Patient Care Gaps

09:03 DIY Healthcare Anxiety

12:50 Balancing Medicine and Lifestyle for Diabetes

15:42 Compassionate Listening in Patient Care

17:38 "Multivitamins and Creatine Benefits"

20:51 Patient Engagement Through Drug Advertising

24:35 Lack of Care Coordination Issues

29:10 Coordinated Care Essential for Patients

32:23 Methylene Blue: Health Trend Risks

36:28 Addressing Sexual Health Stigma

40:03 Affordable Stem Cell and PRP Treatments

41:16 "Exploring Low Dose Naltrexone"

44:43 "Introducing the Popkin Method"

You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected].

Podcast Website - https://thepopkinmethod.com/

Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

Podcast Partner - TopHealth - https://tophealth.care/

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Most people are stuck in a broken system. They have one doctor for weight, another for hormones, a therapist for stress - and a dozen half-baked supplements from the internet.

It doesn’t have to be this way.

Welcome to The Popkin Method - the podcast that finally connects the dots. Hosted by Matthew C. Popkin, M.D. - board-certified internist and functional medicine expert - this show is your guide to personalized, physician-led care that actually makes sense.

One doctor. One coordinated plan. And finally, the full picture of what’s going on with your body.

You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected].

Podcast Website - https://thepopkinmethod.com/

Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

Podcast Partner - TopHealth - https://tophealth.care/

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”