JACC is proud to present research from the PROCTOR trial, and in this video interview with JACC Associate Editor Yousif Ahmad, MD and author Ruben W. de Winter, MD, review the randomized study comparing PCI of native coronary arteries versus saphenous vein grafts in patients with prior CABG. Contrary to expectations, the trial found that at one year, patients treated with vein graft PCI had significantly lower rates of major adverse cardiovascular events than those treated with native vessel PCI, challenging current guideline recommendations and highlighting the need for longer-term follow-up.