The primary objective of current research is extending healthspan—the period of time spent in good health—rather than focusing solely on increasing the maximum human lifespan.

• Rationale: Although human lifespan has increased significantly over the past decades, the healthspan has not increased at the same rate.

• The Goal: Researchers are testing compounds that have the potential to delay or reverse aging processes to optimise the healthspan by delaying the onset of aging-related diseases.

• Current Reality: There is currently no proven drug or supplement that extends human lifespan demonstrated in a long-term human randomised controlled trial. According to recent expert analysis, near-term increases of 10 or more years to the average human lifespan from single interventions are unlikely. Incremental improvements, such as adding months or a few years, may be achievable through combinations of interventions as research advances.