The Tennessee Titans fell to 2-12 on the season with a 37-24 loss at San Francisco on Sunday. In that game, three different safeties went down with injuries, and early this week, all three were placed on injured reserve. That means that a secondary that was already something of a patchwork unit will have to plug in some more pieces this Sunday against the Kansas City Chiefs. The good news on defense remains the play of defensive tackle Jeffery Simmons, who is making a strong case for his first All-Pro selection. Kansas City won't have quarterback Patrick Mahomes, a perennial All-Pro who is out with an injury of his own, but his replacement has a history of playing well against the Titans. Meanwhile, Tennessee quarterback Cam Ward continues to navigate his rookie season, delivering a mix of memorable moments and frustrating missteps.