In this engaging episode of "The Science Circuit," we delve into the captivating world of alchemy, exploring its rich history and foundational role in the development of modern chemistry. We trace alchemy's evolution from ancient mysticism and elaborate rituals aimed at transmuting base metals into gold, to its significant impact on scientific thought that paved the way for empirical experimentation and methodology. Through a lively discussion on the quirky personalities and unexpected scientific contributions of historic alchemists like Isaac Newton and Hennig Brand, we unveil how their relentless pursuit of knowledge seeded the transformation of alchemy into the disciplined science of chemistry, reminding us of the thin line between genius and folly in the quest for understanding the natural world.