The Great Siege of Malta (1565) was an epic clash between the Ottoman Empire and the Knights of St. John, a small but determined force defending the strategic island of Malta. Facing overwhelming odds, the knights and Maltese citizens held their ground in a brutal months-long siege, marked by intense battles, clever fortifications, and fierce resilience. In this episode, we will be examining how this pivotal struggle became a defining moment in the conflict between European and Ottoman forces, altering the course of Mediterranean history and symbolizing the enduring power of courage and unity in the face of adversity.