For 15 years Joe Landson lived with a mysterious illness—one that is little understood and completely lacking in effective treatment. Joe is one of an estimated 30 million people around the world who has suffered from chronic fatigue syndrome, also known as myalgic encephalomyelitis, or ME. For Joe, and so many others, that means enduring aching, injured bodies and debilitating exhaustion. Compounding their illness is the stigma around it. So often doctors and even loved ones doubt what Joe calls, "a disease no one can see."