A variety of dyes, including ethidium bromide, SYBR Green II stain, YOYO-1, methylene blue, acridine orange, are available for sensitive fluorescence-based detection of RNA in the solution. The fluorescence assay allows detection of as little as 1.0 ng/ml RNA in a standard fluorometer, filter fluorometer, or fluorescence microplate reader.https://mrna.creative-biolabs.com/rna-fluorescence-assay.htm