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In the absence of whole blood, if I had to choose between PRBC's or plasma in the prehospital environment for the bleeding patient with coagulopathy, and didn't get to carry both, I would choose (freeze-dried) plasma as the product to carry. Why is this? What reasoning is there to support this?

In trauma, our concern is not just the oxygen carrying capacity in resuscitation. It is also to fix the trauma-induced coagulopathy, the endothelial glycocalyx damage, and more. PRBC's make these worse by diluting the concentration of clotting factors in favor of adding O2-carrying capacity. Plasma gives us back the ability to clot and more. 

Join me in this episode as I present the evidence that would support these claims.