In this edition of the “Peer to Peer” audiocast series, Dr. Vincent DeLeo speaks with Dr. Ted Rosen about the dermatologist’s role in the treatment and diagnosis of syphilis. Dr. Rosen shares current data on the incidence of syphilis in the United States and discusses some of the driving factors behind what has become an epidemic over the last 5 years. He also lists some common skin findings associated with syphilis and explains that, as the only specialists of infectious and noninfectious diseases of the anogenital skin, dermatologists play a crucial role in managing the growing number of syphilis patients.