One pattern keeps showing up in the hundreds of conversations I have with CEOs and clinical innovation leaders: the companies that last are the ones that stay in service of the human relationship. Dr. Louise Chang, Global VP of Clinical Strategy at Elsevier and practicing internal medicine physician, is one of the clearest examples of that principle in action.
"What if AI could actually take the jargon and confusion out of healthcare — so patients and clinicians could finally talk like real people?"
Louise has spent 20+ years asking that exact question. She's building toward AI that bridges the gap between the clinician's workflow and the patient's journey, making care feel more human, not less.
She's moved through startups and scale-ups, nonprofit and for-profit, consumer to provider to payer. And she's watched wave after wave of hype roll through the industry. What she's learned: staying grounded matters more than staying ahead.
Episode Key Moment Highlights:
- [00:05:26] Healthcare AI today: why we're seeing a wide range of outcomes, from "working fast and failing fast" to genuine clinical value at the point of care.
- [00:06:37] ClinicalKey AI in action: how physicians are using it to access patient-specific insights instantly, enabling quick decisions and deeper learning at the same time.
- [00:08:22] The Glow Up for 2026: Louise's vision for AI that doesn't flash — it smooths, bridging the patient and clinician workflow so care actually feels more connected.
- [00:10:18] Closing the care loop: Louise and Nathan align on the big idea — patient AI research and clinician AI tools eventually speaking the same language.
- [00:13:39] Contact lenses, not glasses: Embedding AI so naturally into clinical workflows that it stops feeling like a tool and starts feeling like part of you.
Louise is the clinician who became the strategist — the translator between how medical minds work and how product teams build. Her personal mission is making sure someone is on the clinician's side, and that drives everything she does.
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About Our Guest:
Louise Chang, MD, FACP is a physician executive and internal medicine physician with over 20 years of experience at the intersection of clinical care, digital health, and healthcare innovation. She currently serves as Global Vice President of Clinical Strategy & Partnerships at Elsevier, where she leads clinical strategy for a global portfolio of evidence-based clinical decision support and workflow solutions, including the development of responsible, AI-enabled tools used by clinicians.
Dr. Chang has held senior clinical and product leadership roles across startups, scale-ups, and established organizations, including Babylon Health, WebMD, and the American Cancer Society.
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