The sermon emphasizes that wisdom bestows lasting value, extending beyond earthly happiness and treasures to encompass honor, peace, and pleasantness. It contrasts worldly validation with the profound satisfaction of divine approval, drawing parallels to the Apostle Paul's life, marked by hardship and rejection for the sake of Christ. The message underscores that true peace and contentment stem from trusting God, renewing one's mind, and seeking His guidance, rather than relying on fleeting worldly pleasures or external validation, ultimately leading to an eternal reward and a life marked by God's favor.