Three days after launch, Washington pulled the plug on Claude's two most powerful models.

Run time: 5:38

In today's episode:

1. U.S. government forces Anthropic to disable Fable 5, Mythos 5
2. General chatbots beat dedicated medical AI tools in Nature Medicine
3. SIIM: AI nails the numbers, fumbles the judgment
4. First AI-formulated drug enters a Phase 1 trial
5. Topol: 44 trials, still not standard practice
6. Anthropic credit split and model retirements go live today
7. GPT-5.6 and Gemini 3.5 Pro still stuck in preview

TL;DR:

• Washington issued Anthropic an export-control order three days after launch, forcing it to disable Fable 5 and Mythos 5 for all customers — the model biomedical labs were using for drug design is gone for now.
• A Nature Medicine head-to-head found general-purpose LLMs beat OpenEvidence and UpToDate Expert AI across all three test rounds, with clinicians preferring them; the dedicated tools failed on clarity and safety-critical omissions.
• Radiologists at SIIM 2026 confirmed top LLMs exceed 95% on numerical extraction from scans but still make confident medical-knowledge errors — arithmetic isn't the weak link, judgment is.

Sources cited:

• Nature Medicine
• AuntMinnie
• Contract Pharma
• Medscape
• Ground Truths
• Crescendo AI news roundup
• Anthropic
• Releasebot
• Essa Mamdani

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