Science Society

The World of Genetic physical unclonable functions and Cellular Identity with Dr. Bleris


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Join us in this episode with Dr. Bleris as we dive into the fascinating world of genetic, physical unclonable functions (PUFs) in human cells. PUFs are physical entities that provide a unique and irreproducible identifier for the artifact in which they are embedded. Originally popularized by the electronics industry, PUFs use the inherent physical variations of semiconductor manufacturing to establish intrinsic security measures for attesting integrated circuits.

Inspired by silicon PUFs, Dr. Bleris and his team have embarked on the creation of the first generation of genetic PUFs in human cells. These PUFs are shown to be robust, unique, and unclonable, making them virtually impossible to replicate. Moreover, the team's groundbreaking work with CRISPR-engineered PUFs (CRISPR-PUFs) opens new possibilities for establishing provenance attestation protocols.

This episode sheds light on a new frontier in cell biology, genetic engineering, and identity security. You'll gain insights into the application of genetic PUFs, the potential of CRISPR-PUFs, and the future of biosecurity in this riveting discussion with Dr. Bleris.

Keywords: Dr. Bleris, Genetic PUFs, Physical Unclonable Functions, Silicon PUFs, Human Cells, CRISPR-PUFs, Provenance Attestation Protocols, Biosecurity, Genetic Engineering, Cell Biology.

https://doi.org/10.1126/sciadv.abm4106 Genetic physical unclonable functions in human cells

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Science SocietyBy Catarina Cunha