The Yellow Emperor's Classic of Internal Medicine, Chapter 16, explores diagnostic principles in traditional Chinese medicine. Qibo, responding to the Yellow Emperor's inquiries, details the seasonal flow of human energy (qi) through the body's organs and the appropriate acupuncture techniques for each season. The text further explains the dangers of improper needling, emphasizing the crucial avoidance of vital organs. Finally, it describes the terminal symptoms associated with imbalances in the twelve meridians, offering insights into end-of-life signs within this medical framework.