This Chapter is a dialogue from the Yellow Emperor’s Classic of Internal Medicine, exploring the causes and treatments of wei (atrophy disorders). Qi Bo, a renowned physician, explains how imbalances in the five organs—lungs, heart, liver, spleen, and kidneys—lead to different types of atrophy, manifesting in specific symptoms and physical signs. He further details how these imbalances arise from various factors, including emotional distress, environmental exposure, and excessive activity. Finally, Qi Bo emphasizes the importance of the Yangming channel in treating wei, advocating for a holistic approach that balances the body's energy flow and strengthens specific acupuncture points.