This Chapter from The Yellow Emperor’s Classic of Internal Medicine details the relationship between the skin and the body’s meridians. It describes twelve distinct skin regions, each connected to a specific meridian, explaining how illness begins in the skin and progresses through the network vessels and meridians to the internal organs. The text emphasizes the diagnostic importance of skin color and texture changes in relation to meridian imbalances and the resulting diseases. A dialogue between the Yellow Emperor and Qi Bo reveals a system of understanding illness based on the flow of energy through the body's channels. The condition of the skin provides essential clues to identifying and treating disease.