Botox is the most popular procedure in all of cosmetic surgery.  About 10 million people in the US have Botox every year.  While the term "Botox" has become a generic term, there's actually 6 drugs that have Botox like effects - Xeomin, Dysport, Jeuveux, Daxxify, and Letybo are the others.  These drugs all work basically the same way.  But now Abbvie, the company that markets Botox, has applied to the FDA for approval of a new short acting Botox-like drug.  This one, called TrenibotulinumtoxinE (TrenibotE), works within hours (not days), but only lasts 2-3 weeks (instead of 3-4 months).  The only way this one makes sense to me is to mix TrenibotE with Botox to create a hybrid drug that works immediately and lasts 4 months.  But I would expect the costs to be significantly higher than either drug alone.  Watch for this combo in 2026! And listen to this show for the advance notice on the newest advances in cosmetic surgery.