This essay chronicles the history of toothbrushing, tracing its evolution from ancient civilizations' use of rudimentary tools like chewing sticks and herbal powders to the modern toothbrush and fluoride toothpaste. The text explores diverse cultural practices, including the Islamic miswak and Ayurvedic neem sticks, and highlights the roles of 18th-century inventions, 20th-century advertising, and public health campaigns in establishing toothbrushing as a widespread global habit. It emphasizes the ingenuity of past methods and the scientific advancements that have shaped contemporary oral hygiene. Finally, it connects modern practices to the ancient traditions from which they originated.