Base by Base - Music

Threads of the Mind


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This release contains only the music track from Base by Base Episode 297.

Song title: Threads of the Mind
Original Base by Base episode: 297: Bi-allelic FSD1L variants disrupt mitotic spindle and ciliogenesis in an L1-like neurodevelopmental disorder
Original episode link: https://basebybase.com/episodes/fsd1l-microtubule-ciliogenesis

Article metadata:
Article title: Bi-allelic variants in FSD1L cause a neurodevelopmental disorder overlapping with L1 syndrome
Journal: The American Journal of Human Genetics, Corrected proof. doi:10.1016/j.ajhg.2026.01.014
DOI: 10.1016/j.ajhg.2026.01.014
Reference: Serpieri V., Vezain-Mouchard M., Orsi A., et al. Bi-allelic variants in FSD1L cause a neurodevelopmental disorder overlapping with L1 syndrome. The American Journal of Human Genetics. 113, 1–16 (March 5, 2026). https://doi.org/10.1016/j.ajhg.2026.01.014

Lyrics:
Verse 1
In the quiet lab, under glass and light,
tiny threads spin, trying to set things right,
a keeper on the spindle, an antenna's friend,
without its steady touch, the pattern frays and bends

Pre-Chorus
Stem cells stall on the edge of becoming,
spheres fold in, the bright plans stop humming,
images whisper halls that widen and hollow,
we hold those images close and try not to follow

Chorus
We trace the broken threads, name the silence in the glow,
we watch the tiny antennas shorten, the currents slow,
but in the dark there rises a signal we can hold,
and light becomes the language that teaches the cold

Verse 2
Microscopes show the spindle's trembling hands,
cells that once would reach now cannot make their plans,
axons lose their compass, bridges fail to grow,
the quiet architecture moves too slow

Bridge
Not a single answer, only threads and questions cast,
each image, each embryo, a story from the past,
we map the fragile pattern and listen to the mind,
searching for the small, steady thing that ties the line

Final Chorus
We trace the broken threads, give them a careful name,
from short cilia to widened halls, we keep the flame,
somber but steady, the finding holds its light,
and in that careful watching we find our way through night

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Base by Base - MusicBy Gustavo Barcelos Barra