In this conversation, Sharon Polsky and Dr. Jones discuss the complexities of weight management, emphasizing that being overweight is often not the individual's fault due to hormonal influences. They explore the roles of GLP-1 medications, leptin, ghrelin, and insulin in weight loss, and the importance of a holistic approach that includes lifestyle changes and medical interventions. The discussion also highlights the need for better understanding and testing of metabolic health, particularly insulin resistance, and the impact of fasting on hormone regulation. In this conversation, Sharon Polsky and Dr. J delve into various aspects of weight management, focusing on fasting, the importance of mindset, and the role of GLP-1 medications. They discuss the ten pillars of lasting weight loss, the significance of microdosing, and the necessity of self-reflection in achieving health goals. The dialogue emphasizes the importance of coaching and the dynamic nature of health and wellness, encouraging listeners to explore their motivations and emotional connections to weight loss.