Malaria is the most deadly vector-borne disease in the world, and physicians need to be current on its biology, global disease burden, and advancing treatments. Dr. William Collins, senior biomedical research scientist at the Centers for Disease Control and Prevention, has been a leading expert on malaria and antimalarial vaccine developments for the past 50 years. He joins host Dr. Mary Leuchars to update listeners on the cycle of disease transmission, scope of burden across the world, and the path toward prevention and vaccine development.