What were the medical firsts in Sheffield over the last 200 years? We set out to find these in the Overend-Knight Medical History Podcast – named after two founding figures of medical education in Sheffield. As the University of Sheffield's medical school approaches its bicentenary in 2028, each episode will feature medical discoveries discussed by scientists, medical experts and historians. Find out about the personalities involved, life in Sheffield over the past 200 years, scientific research discoveries and where some of the medical treatments we take for granted today actually came from.