The Transformed Minds Pod

Tranq Alert: What Every Clinician Should Know About Xylazine


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Xylazine, an animal tranquilizer not approved for human use, is increasingly found in street opioids, complicating overdoses and causing devastating wounds. In this episode, we unpack the evidence:

– Why naloxone often fails
– The unique dangers of xylazine toxicity
– What the latest research reveals about toxicity, dependence, withdrawal, and treatment
– Real-world evidence-based recommendations

Based on the 2025 systematic review by Owusu et al.

This is urgent. This is real. Listen and be informed.

#TheTransformedMindsPodcast #Xylazine #HarmReduction #AddictionPsychiatry


Show resource links:Owusu P, et al. Management of Xylazine Toxicity, Overdose, Dependence and Withdrawal: A Systematic Review. 2024.https://mattersnetwork.org/request-test-strips/https://mattersnetwork.org/supplies/#vendingmachineshttps://www.health.ny.gov/diseases/aids/general/opioid_overdose_prevention/training_calendar.htmhttps://providerdirectory.aidsinstituteny.org

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The Transformed Minds PodBy thetransformedmindspod