Dr. Cordero-Baez, MD, Infectious Diseases Fellow at the Morsani USF College of Medicine, presents a lighthearted (and Bad Bunny-inspired) look at travel medicine recommendations for Puerto Rico, a popular travel destination (and his home country) in the Caribbean. Dr. Cordero starts by taking a close look at Dengue, for which cases experienced a surge on the island as recently as in 2024. He then discusses Zika virus, including the viruses epidemiology, transmission vectors, clinical manifestations, and complications. Chikungunya virus is also briefly discussed. He closes by discussing ciguatera poisoning and several other transmissible syndromes.