Overview

1. Troponin I
   
   1. Normal value range
   2. Pathophysiology
   3. Special considerations
   4. Elevations in lab values

Nursing Points General

1. Normal value range
   
   1. Typically less than 0.035 ng/mL or less
   2. Can vary among institutions
   3. Has to be greater than the 99th percentile
2. Pathophysiology
   
   1. Troponin is released during myocardial cell damage
   2. Decreased perfusion causes myocardial cell damage
   3. Causes of myocardial cell damage
      
      1. Myocardial infarction
      2. Demand ischemia
         1. Cardiogenic
            
            1. ACS
         2. Noncardiogenic
            
            1. Sepsis
            2. Renal failure
            3. Extreme exercise