In this episode, we delve into the final results of the Phase 3 METIS study, published in the International Journal of Radiation Oncology, Biology, Physics in 2026, based on an abstract. This study investigated the efficacy and safety of Tumor Treating Fields (TTFields) when used in conjunction with stereotactic radiosurgery (SRS) for patients with non-small cell lung cancer brain metastases (NSCLC BM). The research aimed to extend time to intracranial progression while minimizing neurotoxicity, building on TTFields' known anti-cancer mechanisms. We discuss the study design, patient population, and critical findings that could influence future treatment paradigms for this challenging condition. Please note this podcast is for informational purposes and does not constitute medical advice.