Because ethanol is too small of a molecule for the body to make antibodies to, there really is no such thing as an "alcohol allergy," but that doesn't mean patients can't have a reaction to substances found within alcohol. In this episode of ImmunoCAST, we address the clinical challenge of distinguishing between alcohol intolerance and true allergy. Tune in as we explore histamine intolerance, sulfite sensitivity, and ALDH2 deficiency, as well as hidden allergens in alcoholic beverages, the role of alcohol as a cofactor in allergic reactions, and specific allergens found in wine and beer. Discover how to diagnose and manage alcohol-related reactions by learning more about the importance of detailed patient history, specific IgE testing, and the implications of enzyme deficiencies.

Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e10.html?cid=0ct_3pc_05032024_9SGOV4