this episode delivers an in-depth look at calciphylaxis—a rare, life-threatening condition that primarily affects patients with kidney failure on dialysis. You’ll learn:

• How calcium buildup devastates small blood vessels and tissue
• The cellular misprogramming that mimics bone formation in vessels
• Risk factors including mineral imbalances, obesity, and diabetes
• Why diagnosis is difficult and hinges on a skin biopsy
• The role—and controversy—surrounding sodium thiosulfate in treatment

An essential listen for clinicians and caregivers navigating the complexities of this painful and poorly understood condition.