The sermon explores the origin and nature of suffering, tracing it back to the fall and highlighting the roles of Satan, selfishness, sin, and divine judgment. It emphasizes that while suffering is inevitable, God's grace is always sufficient to help individuals endure and even find strength in their weakness, drawing parallels to the experiences of biblical figures like Joseph and Paul. Ultimately, the message encourages listeners to boldly approach God's throne of grace, seeking mercy and the necessary assistance to navigate life's challenges with faith and resilience, finding that God's resources are available to help in times of need.