Many harmful chemicals like BPA are being phased out of plastics. But the big question is: are the replacements actually safer for the planet? Industries are switching to "alternative" bisphenols, yet we currently lack sufficient information on whether these new options are toxic to aquatic life or if they will persist in the environment over time. A specialised research initiative is now dedicated to closing this knowledge gap. The focus is on using advanced methods—such as sophisticated computer modeling and targeted laboratory tests on simple aquatic organisms—to rapidly screen these alternatives for environmental risks. Active planning for these crucial studies is currently underway, with the specific scientific protocols being finalised right now. Investigating these substitutes before they become widespread is essential for ensuring that moving away from BPA truly leads to a cleaner environment.