Join host Lucien Graves as he catalogs diseases medicine cannot yet name—viruses at the species barrier, resurgent plagues, and phantom pathogens emerging from the unknown. Unknown Conditions reveals unsettling patterns in infections lurking at the edges of scientific understanding.

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Lucien Graves examines the alarming resurgence of diseases humanity believed conquered—measles, tuberculosis, and cholera. This episode explores antibiotic resistance, vaccine hesitancy, and the fragile infrastructure protecting us from pathogens that never truly disappeared, only waited for our complacency to return.

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This content was created in partnership and with the help of Artificial Intelligence AI

This episode includes AI-generated content.

Lucien Graves examines Disease X, the WHO's placeholder for unknown future pandemics. From its 2017 designation through COVID-19's emergence and ongoing preparedness efforts, this episode explores how scientists prepare for pathogens that don't yet exist—and why the next outbreak may arrive when we're looking elsewhere.

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This content was created in partnership and with the help of Artificial Intelligence AI

This episode includes AI-generated content.

Lucien Graves examines zoonotic spillover—when animal diseases jump to humans—exploring Nipah virus in Bangladesh and resurgent Oropouche fever in Brazil. Deforestation, climate change, and wildlife trade are accelerating these deadly crossings and opening doors to the next pandemic.

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This content was created in partnership and with the help of Artificial Intelligence AI

This episode includes AI-generated content.