Hear how a team of interdisciplinary experts solved the structure of LRRK2, a gene found to be mutated in Parkinson’s disease, and how their discovery is guiding the way for new targeted therapeutics. Series: "Innovations Shaping the Future of Parkinson's Disease Treatment " [Health and Medicine] [Show ID: 37039]

Unlocking LRRK2: A New Drug Target - Innovations Shaping the Future of Parkinson's Disease Treatments

Explore the world of neuroscience and the secrets of the brain. Discover how the brain works, technologies to harness brain power, ways to treat disease, and more.

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What can you do today to improve or maintain your brain health? Sarah Banks, Ph.D., an expert in healthy aging, dementia, and Alzheimer's disease, explores risk factors and offers practical tips for enhancing brain health. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 39387]

Can We Avoid Cognitive Decline with Age?

Claudia H. Kawas, M.D., addresses Alzheimer's disease and related conditions in older adults, noting the challenge of accurate diagnosis and the resemblance of other brain conditions to Alzheimer's. She introduces "resistance" and "resilience," explaining how some individuals remain cognitively intact despite brain changes. Kawas suggests declining dementia risk due to improved vascular health management, emphasizing the complexity of cognitive decline and the need for further research. Series: "Brain Channel" [Health and Medicine] [Science] [Show ID: 39532]

Cognitive Aging In The Oldest Old: Resilience And Risk Revealed

Alzheimer’s disease is a major health crisis that is projected to become an even larger threat in the coming decades. According to the National Institute on Aging, the number of Americans 65 and older with Alzheimer’s could rise from 5.8 million in 2020 to 13.8 million by 2050. Given the severity of this health crisis and the toll it takes on patients, their families and society, we must be prepared today to address the needs of tomorrow. Dean Frank LaFerla of UC Irvine's School of Biological Sciences presents an overview of the state of Alzheimer’s disease research. Following his presentation, the panel discusses emerging trends in research, care and the upcoming challenges we will face and how we might mitigate them. [Health and Medicine] [Show ID: 38660]

Looking to a Future Without Alzheimer's

Thomas C. Südhof, M.D., Stanford University, discusses facets of the fundamental cell biology of ApoE and APP analyzed in stem cell-derived human neurons.  Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38405]

Modeling Neurological Conditions Using Stem Cell-Derived Neurons: ApoE and APP in Alzheimer's Disease with Thomas C. Südhof - Sanford Stem Cell Symposium 2022

Dr. Songi Han, professor in the Department of Chemistry, Biochemistry and Chemical Engineering at UC Santa Barbara, talks about her research into the function of proteins in the body and how changes like protein Tau tangles can lead to neurological diseases like Alzheimer's. Series: "GRIT Talks" [Health and Medicine] [Science] [Show ID: 37869]

Unlocking LRRK2: A New Drug Target - Innovations Shaping the Future of Parkinson's Disease Treatments

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