Though rare in the general population, hyperkalemia often occurs among patients with CKD, particularly among older individuals in advanced stages of the disease. Patients with hyperkalemia are predisposed to cardiac hyperexcitability & depression, both of which can be fatal, particularly if not treated rapidly. This educational activity will provide a review of hyperkalemia, including a discussion of the associated health burden, risk factors, & evidence-based management strategies. In addition, recent FDA approvals & clinical trial data supporting improved outcomes in high-risk patients will also be considered.