The emergence and subsequent spread of the Delta variant has led several countries, most notably the United States, into adopting more stringent health and safety protocols. On 29 July 2021, President Biden declared that the US government would be imposing vaccination requirements in certain cases and offering additional incentives for its citizens to be vaccinated. Following this announcement, TMT Talk revisits the important legal aspects of vaccinations, as they apply to the TMT sector. Kate Alexander, Susan Eandi, and Julia Wilson discuss key considerations for companies when it comes to vaccination requirements and workplace safety protocols, as well as their perspective on how to best approach vaccine mandates.