The Healthy Enterprise

Vision Meets Innovation: Leading in Life Sciences with David Esposito


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In this episode, we interview David Esposito, an experienced healthcare CEO with a background in both large pharma and early-stage biotech. David discusses his career journey, insights into leading and scaling healthcare companies, and the challenges and opportunities in developing innovative therapies for diseases of the eye. He also shares his perspective on leadership, team building, and the importance of maintaining a focus on patient outcomes.

Chapters/Timestamps:

  • 00:00 - Introduction and David Esposito's Background
  • 02:09 - ONL Therapeutics and its Focus
  • 09:05 - David Esposito’s Career Journey
  • 24:47 - Leadership and Team Building
  • 32:35 - Challenges in Biotech and Company Growth
  • 48:22 - Marketing and Clinical Trial Enrollment
  • 58:52 - Funding and Future Outlook
  • 1:09:09 - Inspiration and Advice
  • 1:19:31 - The Future of Healthcare Innovation


Guest Information:

  • Guest's Name: David Esposito
  • Guest's Title/Position: CEO
  • Company/Affiliation: ONL Therapeutics
  • Guest's Bio: David Esposito is an experienced healthcare CEO with over thirty years in the industry. He has a background in large pharma and has built and scaled multiple early to mid-stage life science companies. Currently, he is the CEO of ONL Therapeutics, a mid-stage biotech company focused on developing therapies for diseases of the eye.


Links and Resources:

  • ONL Therapeutics: https://onltherapeutics.com/
  • RA Capital: https://www.racap.com/
  • Andreessen Horowitz: https://a16z.com/



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The Healthy EnterpriseBy Heath Fletcher