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Share Vitamin D for Longevity—or a Lesson in Over-Supplementation? What a Sept-2025 Case Teaches Us About Vitamin D Toxicity
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Vitamin D for Longevity—or a Lesson in Over-Supplementation? What a Sept-2025 Case Teaches Us About Vitamin D Toxicity
Resources:
Vitamin D testing options
Sleep OS Hormones: https://thelongevityvault.com/sleep-os/hormones/
A new case published in The Journal of the Norwegian Medical Association (Sept 2025) describes a healthy man who developed acute kidney failure after six months of self-supplementing vitamin D.
This short episode unpacks what happened, why “moderate” doses can accumulate unpredictably, and how genetics, cofactors, and testing shape individual responses.
Key points:
* Even within guideline limits, metabolism and calcium handling can differ dramatically.
* Vitamin D acts as a hormone precursor, not a simple nutrient—its safe range is narrower than most assume.
* Testing twice a year provides reliable feedback on dose and response.
Listen for:
How to interpret the case, what to learn from it, and how to personalize your own vitamin D strategy before supplementing.
📫 If you’d like more evidence-based guides like this—covering hormones, metabolism, and sleep—subscribe to The Longevity Vault.
This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit thelongevityvault.substack.com/subscribe
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By Kat Fu, M.S., M.S.Resources:
Vitamin D testing options
Sleep OS Hormones: https://thelongevityvault.com/sleep-os/hormones/
A new case published in The Journal of the Norwegian Medical Association (Sept 2025) describes a healthy man who developed acute kidney failure after six months of self-supplementing vitamin D.
This short episode unpacks what happened, why “moderate” doses can accumulate unpredictably, and how genetics, cofactors, and testing shape individual responses.
Key points:
* Even within guideline limits, metabolism and calcium handling can differ dramatically.
* Vitamin D acts as a hormone precursor, not a simple nutrient—its safe range is narrower than most assume.
* Testing twice a year provides reliable feedback on dose and response.
Listen for:
How to interpret the case, what to learn from it, and how to personalize your own vitamin D strategy before supplementing.
📫 If you’d like more evidence-based guides like this—covering hormones, metabolism, and sleep—subscribe to The Longevity Vault.
This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit thelongevityvault.substack.com/subscribe