Dr. B. Douglas Smith, MD, Associate Professof of Oncology, Division of Hematologic Malignancies at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins in Baltimore, MD, will present case scenarios which will address: developing an approach to treatmet for patietns newly diagnosed with CML, develop effective monitoring strategies for CML patients--assessing for early opportunities to adjust therapy to maxiize tolerability and response; and describe the role of allogeneic stem cell transplantation