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Dive into the world of pharmacology as we explore how warfarin interacts with antibiotics at a molecular level. This episode highlights the crucial role of CYP2C9 metabolism in regulating S-warfarin and explains why certain antibiotics, like metronidazole and fluconazole, can significantly impact INR levels. We also unpack the challenge of separating true drug-drug interactions from infection-driven effects, giving you a clear look at the science behind these complex interactions. Perfect for pharmacists, clinicians, and anyone fascinated by how drugs work in the body.
By Anthony LauDive into the world of pharmacology as we explore how warfarin interacts with antibiotics at a molecular level. This episode highlights the crucial role of CYP2C9 metabolism in regulating S-warfarin and explains why certain antibiotics, like metronidazole and fluconazole, can significantly impact INR levels. We also unpack the challenge of separating true drug-drug interactions from infection-driven effects, giving you a clear look at the science behind these complex interactions. Perfect for pharmacists, clinicians, and anyone fascinated by how drugs work in the body.